1650-53: Huron survivors of the "Beaver Wars" settle at Lorette under French protection.
1652: Massachusetts General Court licenses traders going from Massachusetts to Acadia.
1654-59: Pierre-Esprit Radisson, French Sieur de Groselliers, encounters a lot of tribes throughout New France, New England, and what's now the U.S. midwest. Adopted by a Mohawk family, who take him to Hudson's Bay. There he changes sides and becomes English, participates in the formation of Hudson's Bay Company, and charter of Rupert's Land to it in 1670, deftly switching country allegiances several times France-England-France-England during the process. Ends up English. Today principally remembered by a hotel named after him in Minneapolis.
c. 1655: One of the coureurs de bois, adventurous, unlicensed fur traders who want to escape company restrictions, explores west of Lake Superior.
1657: Sulpicians, who run missions, come to North America.
1659: A vicar apostolic, the Jesuit-trained Bishop Francois X. de Laval-Montmorency (1623-1708) arrives in Quebec in June as vicar general of the pope to take command of the missions and to found parishes.