See also: 1804 in science, other events of 1805, 1806 in science and the list of years in science.
Exploration April 7 - The Lewis and Clark expedition leaves Fort Mandan, bound for the Pacific Ocean August 9 - Zebulon Pike leaves St. Louis to explore the headwaters of the Mississippi River November 16 - The Lewis and Clark expedition reaches the Pacific Ocean at the mouth of the Columbia River Awards Copley Medal: Humphry Davy Births February 13 - Peter Gustav Lejeune Dirichlet, mathematician (died 1859) May 12 - William Rowan Hamilton, mathematician, physicist, and astronomer (died 1865) December 16 - Isidore Geoffroy Saint-Hilaire, zoologist (died 1861) December 20 - Thomas Graham, chemist (died 1869) Deaths January 23 - Claude Chappe, inventor of the semaphore system (born 1763) December 23 - Pehr Osbeck, Swedish botanist and explorer, pupil of Linnaeus (born 1723)