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The Treaty states that the 49th parallel will form the border of the United States and the British on the mainland. Vancouver Island was an exception that was given to the British in its entirety despite going south of the 49th parallel. The 49th parallel became the US-Canadian border when British Columbia became part of Canada.
The U.S. portion of the region was organized as the Territory of Oregon on August 14, 1848.
In 1859, a defect in the wording of the treaty later led to the Pig War over the ownership of the San Juan Islands.