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ACTH stimulates the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also mineralcorticoids and sex steroids (androgens). Together with ACTH the hormones lipotropin, melanocyte-stimulating hormone (MSH), β-endorphin and met-enkephalin are also released.
The half-life of ACTH in human blood is about 10 minutes.
Addison's disease, adrenoleukodystrophy, Congenital adrenal hyperplasia, Cushing's syndrome, ectopic tumor, HPA Axis, Nelson's syndrome,
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