A phenomenon, opposite to LTP, which has different underlying mechanisms.

LTD is a weakening of the strength of a synapse, in response either to strong stimulation (as in the cerebellum) or to persistent weak stimulation (as in the hippocampus). LTD is thought to result from changes in postsynaptic receptor density, although changes in presynaptic release may also play a role.

Limited Company

LTD is used as abreviation to Limited which indicates that a company is a limited company by English law. There are mainly three types of limited companies: private limited company by shares, private limited company by guarantee, public limited company.