The Mohawk tribe of Native American people lived around the Great Lakes and St. Lawrence River in what is now Canada and the United States. They belonged to the Iroquois confederation. After the pre-historic formation of the Iroquois confederation (Hodenosaunee), the Mohawks became keepers of the Eastern Door, guarding the members against invasions from that direction.

Many current members of the Mohawk tribe live on the Saint Regis Reservation in northern New York.