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The idea that Nero Wolfe was the product of an affair between Sherlock Holmes and Irene Adler (whom Holmes always called "the Woman") in Montenegro in 1892, was published in the Baker Street Journal in 1956 by John D. Clark, and co-opted by William S. Baring-Gould. The creators of Wolfe and Holmes had no such connection in mind. Stout, who had the opportunity to accept or reject the suggestion, did neither.

The Nero Wolfe mysteries have been turned into several movies, including Meet Nero Wolfe (1936), an adaptation of the first Wolfe novel starring Edward Arnold as Wolfe and Lionel Stander as Archie Goodwin, and The League of Frightened Men (1937), an adaptation of the second Wolfe novel starring Walter Connolly and Lionel Stander.
A number of radio series have been made based on the Nero Wolfe stories:
In 1977, Thayer David and Tom Mason starred in a telemovie based on "The Doorbell Rang", intended as the pilot episode for a television series that did not eventuate.
In 1981, William Conrad and Lee Horsley starred in a short-lived television series.
In 2001, Maury Chaykin and Timothy Hutton starred in The Golden Spiders, an telemovie adaptation of the 1953 story of the same name.
This led to an ongoing series.
The first season is available on DVD, and the second season and telemovie are due to be released on DVD in June 2004.Bibliography
Nero Wolfe books by Rex Stout
Nero Wolfe short stories by Rex Stout
Nero Wolfe books by Robert Goldsborough
Books about Nero Wolfe
Wolfe in other media
Cinema
Radio
Television